Gnarus Systems

 
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Cat-SAR Bibliography

Cunningham, A.R., S.L. Cunningham, and H.R. Rosenkranz (2004) Structure activity approach to the identification of environmental estrogens: The MCASE approach. SAR and QSAR in Environmental Research, 15(1): 55-67.

Cunningham, A.R., S.L. Cunningham, D.M. Consoer, S.T. Moss, and M.H. Karol (2005) Development of an information-intensive structure- activity relationship model and its application to human respiratory chemical sensitizers. SAR and QSAR in Environmental Research, 16(3): 273-285.

Cunningham, S.L., A.R. Cunningham, and B.W. Day (2005) CoMFA, HQSAR and molecular docking studies of butitaxel analogues with b-tubulin. Journal of Molecular Modeling, 11(1): 48-54.

Cunningham, A.R., S.T. Moss, S.A. Iype, G. Qian, S. Qamar, and S.L. Cunningham (2008) Structure-activity relationship analysis of rat mammary carcinogens. Chemical Research in Toxicology, 21: 1970-1982.

Cunningham, A.R., D.M. Consoer, S.A. Iype, and S.L. Cunningham (2009) A structure-activity relationship analysis for the identification of environmental estrogens: The categorical-SAR (cat-SAR) approach. In Endocrine Disruption Modeling, J. Devillers, Editor, CRC Press. p. 173-198.

Cunningham, A.R., C.A. Carrasquer, and D.M. Mattison (2009) A categorical structure-activity relationship analysis of the developmental toxicity of antithyroid drugs. International Journal of Pediatric Endocrinology.

Cunningham, A.R., S. Qamar, C.A. Carrasquer, P.A. Holt, J.M. Maguire, S.L. Cunningham, and J.O. Trent (2010) Mammary carcinogen-protein binding potentials: Novel and biologically relevant structure-activity relationship model descriptors. SAR and QSAR in Environmental Research, 21:463-479.

 
 
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Consulting Service

Gnarus Systems offers predictive toxicological assessment of chemicals, SAR model development, and virtual screening on an ad hoc basis.

Direct Access

For larger projects, Gnarus Systems can provide users with secure cloud-based access to the cat-SAR expert system along with validated predictive models.

Complete System

Similar to "Direct Access" with the added advantage that users can update/alter exisitng models as well as produce models with user specific data. In this case, users can develop, validate, and use models based on private or proprietary data.